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Smoking now kills 480,000 Americans each year

For example, writing in the New England Journal of Medicine, Willett, Colditz and Hiatt [5] argued that the PCP was misguided in its emphasis on environmental carcinogens: It is important not to detract from the fact that the major causes of cancer are smoking, overweight, and inactivity . But if talking about environmental carcinogens detracts from attention to smoking, overweight and inactivity, the public, policy-makers and clinicians might be forgiven for concluding that all people need to do to prevent cancer is to change their unhealthy behaviors

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Common digestive causes include acid reflux (GERD), indigestion, excessive gas, oesophageal spasms, or stomach inflammation